Bruno Gottstein Selected Research

Alveolar echinococcosis

1/2022	Albendazole reduces hepatic inflammation and endoplasmic reticulum-stress in a mouse model of chronic Echinococcus multilocularis infection.
10/2021	Accelerated Course of Alveolar Echinococcosis After Treatment With Steroids in a Patient With Autoimmune Encephalitis.
7/2021	Impact on Bile Acid Concentrations by Alveolar Echinococcosis and Treatment with Albendazole in Mice.
1/2021	Digest the Sugar, Kill the Parasite: A New Experimental Concept in Treating Alveolar Echinococcosis.
12/2020	Short communication: Efficacy of albendazole in Echinococcus multilocularis-infected mice depends on the functional immunity of the host.
1/2020	Regulation of hepatic microRNAs in response to early stage Echinococcus multilocularis egg infection in C57BL/6 mice.
1/2019	ALVEOLAR ECHINOCOCCOSIS IN WESTERN LOWLAND GORILLAS (GORILLA GORILLA GORILLA): ALBENDAZOLE WAS NOT ABLE TO STOP PROGRESSION OF THE DISEASE.
12/2018	Immunotherapy of alveolar echinococcosis via PD-1/PD-L1 immune checkpoint blockade in mice.
1/2018	Larval Echinococcus multilocularis infection reduces dextran sulphate sodium-induced colitis in mice by attenuating T helper type 1/type 17-mediated immune reactions.
12/2017	Screening of antigenic vesicular fluid proteins of Echinococcus multilocularis as potential viability biomarkers to monitor drug response in alveolar echinococcosis patients.

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Bruno Gottstein Research Topics

Disease

25	Infections 01/2022 - 02/2002
21	Alveolar echinococcosis 01/2022 - 02/2002
8	Echinococcosis (Hydatid Cysts) 01/2022 - 11/2006
4	Inflammation (Inflammations) 01/2022 - 01/2014
4	Parasitic Diseases (Parasitic Disease) 12/2020 - 01/2010
3	Persistent Infection 01/2018 - 02/2003
2	Neoplasms (Cancer) 01/2021 - 08/2004
2	Eosinophilia 12/2019 - 01/2009
2	Coinfection 02/2003 - 09/2002
1	Autoimmune Diseases of the Nervous System 10/2021
1	Cholestasis 12/2019
1	Rabies (Hydrophobia) 10/2019
1	Filariasis 02/2019
1	Toxocariasis 02/2019
1	Ascariasis 02/2019
1	Vomiting 01/2019
1	Neurologic Manifestations (Neurological Manifestations) 01/2019
1	Asymptomatic Infections 01/2019
1	Dehydration (Water Stress) 01/2019
1	Colitis 01/2018
1	Pain (Aches) 01/2018
1	Fibrosarcoma 11/2016
1	Hepatocellular Carcinoma (Hepatoma) 03/2016
1	Coccidiosis 09/2014
1	Nematode Infections 09/2014
1	Helminthiasis (Helminthiases) 07/2014
1	Airway Obstruction (Choking) 10/2013
1	Babesiosis (Piroplasmosis) 06/2013
1	Necrosis 06/2011
1	Neoplasm Metastasis (Metastasis) 11/2010
1	Weight Loss (Weight Reduction) 09/2010
1	Zoonoses 09/2009
1	Trichinellosis 09/2009
1	Meningoencephalitis 02/2007

Drug/Important Bio-Agent (IBA)

13	AntigensIBA 02/2019 - 02/2002
11	Proteins (Proteins, Gene)FDA Link 01/2022 - 08/2002
9	Albendazole (Albenza)FDA Link 01/2022 - 04/2004
7	EnzymesIBA 12/2019 - 08/2002
7	CytokinesIBA 01/2018 - 01/2010
4	ImmunosorbentsIBA 10/2019 - 08/2002
4	Pharmaceutical PreparationsIBA 12/2017 - 06/2004
3	AntibodiesIBA 02/2019 - 01/2014
3	ChemokinesIBA 10/2018 - 01/2014
3	DNA (Deoxyribonucleic Acid)IBA 01/2014 - 06/2004
2	Biomarkers (Surrogate Marker)IBA 01/2022 - 12/2017
2	Immune Checkpoint InhibitorsIBA 01/2021 - 12/2018
2	Immunoglobulin G (IgG)IBA 02/2019 - 09/2003
2	Formaldehyde (Formol)FDA Link 01/2019 - 02/2007
2	Drinking WaterIBA 01/2018 - 06/2004
2	18S Ribosomal RNAIBA 06/2013 - 02/2007
2	Complement System Proteins (Complement)IBA 08/2010 - 02/2007
2	Phosphates (Orthophosphate)IBA 02/2007 - 02/2003
2	toltrazurilIBA 06/2004 - 10/2002
1	Endoplasmic Reticulum Chaperone BiPIBA 01/2022
1	endoplasmic reticulum glycoprotein p72IBA 01/2022
1	CalreticulinIBA 01/2022
1	SteroidsIBA 10/2021
1	Bile Acids and Salts (Bile Acids)IBA 07/2021
1	SugarsIBA 01/2021
1	MicroRNAs (MicroRNA)IBA 01/2020
1	zinc chloride FDA Link 01/2019
1	Acetic Acid (Vinegar)FDA LinkGeneric 01/2019
1	Sodium Acetate (Sodium Acetate, Anhydrous)FDA LinkGeneric 01/2019
1	Interferon-gamma (Interferon, gamma)IBA 10/2018
1	Interleukin-4 (Interleukin 4)IBA 10/2018
1	Dextrans (Dextran)FDA Link 01/2018
1	SodiumIBA 01/2018
1	Frizzled ReceptorsIBA 11/2016
1	Activins (Activin)IBA 11/2016
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 11/2016
1	Epidermal Growth Factor (EGF)IBA 11/2016
1	Phosphotransferases (Kinase)IBA 11/2016
1	5- chloro- 2- hydroxy- N- (3- (trifluoromethyl)phenyl)benzamideIBA 03/2016
1	salicylanilideIBA 03/2016
1	Interleukin-10 (Interleukin 10)IBA 10/2015
1	Fibrinogen (Factor I)FDA Link 05/2015
1	VaccinesIBA 01/2015
1	SaponinsIBA 01/2015
1	AnthelminticsIBA 09/2014
1	Mebendazole (Anti-Worm)FDA Link 01/2014
1	Fluorodeoxyglucose F18 (Fludeoxyglucose F 18)FDA Link 01/2014
1	Virulence Factors (Pathogenicity Factors)IBA 10/2012
1	InterleukinsIBA 06/2011
1	LipopolysaccharidesIBA 06/2011
1	Genetic Markers (Genetic Marker)IBA 01/2011
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 11/2010
1	Peptides (Polypeptides)IBA 08/2010
1	Interferon-alpha (Interferon Alfa)IBA 01/2010
1	Ribosomal DNA (rDNA)IBA 05/2007
1	ParaffinIBA 02/2007
1	IsoflavonesIBA 11/2006
1	BenzimidazolesIBA 10/2004

Therapy/Procedure

4	Immunotherapy 12/2018 - 01/2015
4	Drug Therapy (Chemotherapy) 10/2004 - 10/2002
2	Therapeutics 01/2022 - 01/2021
1	Aftercare (After-Treatment) 10/2021
1	Laparotomy 10/2019
1	Critical Care (Surgical Intensive Care) 01/2019
1	Palliative Care (Palliative Therapy) 01/2018
1	Blood Transfusion (Blood Transfusions) 09/2010